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Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by synaptic loss that leads to the development of cognitive deficits. Synapses are neuronal structures that play a crucial role in memory formation and are known to consume most of the energy used in the brain. Interestingly, AMP...
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| Опубликовано в: : | Cell Death Dis |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399353/ https://ncbi.nlm.nih.gov/pubmed/30833547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1464-x |
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