Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by synaptic loss that leads to the development of cognitive deficits. Synapses are neuronal structures that play a crucial role in memory formation and are known to consume most of the energy used in the brain. Interestingly, AMP...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Domise, Manon, Sauvé, Florent, Didier, Sébastien, Caillerez, Raphaëlle, Bégard, Séverine, Carrier, Sébastien, Colin, Morvane, Marinangeli, Claudia, Buée, Luc, Vingtdeux, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399353/
https://ncbi.nlm.nih.gov/pubmed/30833547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1464-x
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