AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation

Although the brain accounts for only 2% of the total body mass, it consumes the most energy. Neuronal metabolism is tightly controlled, but it remains poorly understood how neurons meet their energy demands to sustain synaptic transmission. Here we provide evidence that AMP-activated protein kinase...

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Veröffentlicht in:iScience
Hauptverfasser: Marinangeli, Claudia, Didier, Sébastien, Ahmed, Tariq, Caillerez, Raphaelle, Domise, Manon, Laloux, Charlotte, Bégard, Séverine, Carrier, Sébastien, Colin, Morvane, Marchetti, Philippe, Ghesquière, Bart, Balschun, Detlef, Buée, Luc, Kluza, Jérôme, Vingtdeux, Valérie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203244/
https://ncbi.nlm.nih.gov/pubmed/30368077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.10.006
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