Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells

Knowledge of protein signalling pathways in the working cell is seen as a primary route to identifying and developing targeted medicines. In recent years there has been a growing awareness of the importance of the mTOR pathway, making it an attractive target for therapeutic intervention in several d...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Ahmed, Abdullah R., Owens, Raymond J., Stubbs, Christopher D., Parker, Anthony W., Hitchman, Richard, Yadav, Rahul B., Dumoux, Maud, Hawes, Chris, Botchway, Stanley W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399282/
https://ncbi.nlm.nih.gov/pubmed/30833605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39410-z
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