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Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function

Inherited hearing loss is associated with gene mutations that result in sensory hair cell (HC) malfunction. HC structure is defined by the cytoskeleton, which is mainly composed of actin filaments and actin-binding partners. LIM motif-containing protein kinases (LIMKs) are the primary regulators of...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Fang, Qiaojun, Zhang, Yuhua, Da, Peng, Shao, Buwei, Pan, Haolai, He, Zuhong, Cheng, Cheng, Li, Dan, Guo, Jiaqi, Wu, Xiaohan, Guan, Ming, Liao, Menghui, Zhang, Yuan, Sha, Suhua, Zhou, Zikai, Wang, Jian, Wang, Tian, Su, Kaiming, Chai, Renjie, Chen, Fangyi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399249/
https://ncbi.nlm.nih.gov/pubmed/30833597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39769-z
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