Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function

Inherited hearing loss is associated with gene mutations that result in sensory hair cell (HC) malfunction. HC structure is defined by the cytoskeleton, which is mainly composed of actin filaments and actin-binding partners. LIM motif-containing protein kinases (LIMKs) are the primary regulators of...

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Publicado no:Sci Rep
Main Authors: Fang, Qiaojun, Zhang, Yuhua, Da, Peng, Shao, Buwei, Pan, Haolai, He, Zuhong, Cheng, Cheng, Li, Dan, Guo, Jiaqi, Wu, Xiaohan, Guan, Ming, Liao, Menghui, Zhang, Yuan, Sha, Suhua, Zhou, Zikai, Wang, Jian, Wang, Tian, Su, Kaiming, Chai, Renjie, Chen, Fangyi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399249/
https://ncbi.nlm.nih.gov/pubmed/30833597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39769-z
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