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Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function

Inherited hearing loss is associated with gene mutations that result in sensory hair cell (HC) malfunction. HC structure is defined by the cytoskeleton, which is mainly composed of actin filaments and actin-binding partners. LIM motif-containing protein kinases (LIMKs) are the primary regulators of...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Fang, Qiaojun, Zhang, Yuhua, Da, Peng, Shao, Buwei, Pan, Haolai, He, Zuhong, Cheng, Cheng, Li, Dan, Guo, Jiaqi, Wu, Xiaohan, Guan, Ming, Liao, Menghui, Zhang, Yuan, Sha, Suhua, Zhou, Zikai, Wang, Jian, Wang, Tian, Su, Kaiming, Chai, Renjie, Chen, Fangyi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399249/
https://ncbi.nlm.nih.gov/pubmed/30833597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39769-z
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