Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes

Autophagy is the major mechanism involved in degradation and recycling of intracellular components, and its alterations have been proposed to cause beta cell dysfunction. In this study, we explored the effects of autophagy modulation in human islets under conditions associated to endoplasmic reticul...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Bugliani, M., Mossuto, S., Grano, F., Suleiman, M., Marselli, L., Boggi, U., De Simone, P., Eizirik, D. L., Cnop, M., Marchetti, P., De Tata, V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399112/
https://ncbi.nlm.nih.gov/pubmed/30863363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00052
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