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Generalizing a mathematical model of prion aggregation allows strain coexistence and co-stability by including a novel misfolded species
Prions are proteins capable of adopting misfolded conformations and transmitting these conformations to other normally folded proteins. Prions are most commonly known for causing fatal neurodegenerative diseases in mammals but are also associated with several harmless phenotypes in yeast. A distinct...
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| Publicado no: | J Math Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399074/ https://ncbi.nlm.nih.gov/pubmed/30116882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-018-1280-4 |
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