Bicuculline Reduces Neuroinflammation in Hippocampus and Improves Spatial Learning and Anxiety in Hyperammonemic Rats. Role of Glutamate Receptors

Patients with liver cirrhosis may develop minimal hepatic encephalopathy (MHE) with mild cognitive impairment. Hyperammonemia is a main contributor to cognitive impairment in MHE, which is mediated by neuroinflammation. GABAergic neurotransmission is altered in hyperammonemic rats. We hypothesized t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Pharmacol
Päätekijät: Malaguarnera, Michele, Llansola, Marta, Balzano, Tiziano, Gómez-Giménez, Belén, Antúnez-Muñoz, Carles, Martínez-Alarcón, Núria, Mahdinia, Rahebeh, Felipo, Vicente
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Pharmacology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397886/
https://ncbi.nlm.nih.gov/pubmed/30858801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00132
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