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Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS proteins
MCM2-7 proteins provide essential helicase functions in eukaryotes at chromosomal DNA replication forks. During the G1 phase of the cell cycle they remain loaded on DNA but are inactive. We have used recombinant methods to show that the Drosophila MCM2-7 helicase is activated in complex with Cdc45 a...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6396293/ https://ncbi.nlm.nih.gov/pubmed/20122406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.030 |
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