EZH2 cooperates with gain‐of‐function p53 mutants to promote cancer growth and metastasis

In light of the increasing number of identified cancer‐driven gain‐of‐function (GOF) mutants of p53, it is important to define a common mechanism to systematically target several mutants, rather than developing strategies tailored to inhibit each mutant individually. Here, using RNA immunoprecipitat...

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Publicado en:EMBO J
Autores principales: Zhao, Yu, Ding, Liya, Wang, Dejie, Ye, Zhenqing, He, Yundong, Ma, Linlin, Zhu, Runzhi, Pan, Yunqian, Wu, Qiang, Pang, Kun, Hou, Xiaonan, Weroha, Saravut J, Han, Conghui, Coleman, Roger, Coleman, Ilsa, Karnes, R Jeffery, Zhang, Jun, Nelson, Peter S, Wang, Liguo, Huang, Haojie
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396169/
https://ncbi.nlm.nih.gov/pubmed/30723117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899599
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