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Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control pathways
Ribosome stalling triggers quality control pathways targeting the mRNA (NGD: no‐go decay) and the nascent polypeptide (RQC: ribosome‐associated quality control). RQC requires Hel2‐dependent uS10 ubiquitination and the RQT complex in yeast. Here, we report that Hel2‐dependent uS10 ubiquitination and...
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| Udgivet i: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6396155/ https://ncbi.nlm.nih.gov/pubmed/30609991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100276 |
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