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Pharmacological Sequestration of Mitochondrial Calcium Uptake Protects Neurons Against Glutamate Excitotoxicity

Neuronal excitotoxicity which is induced by exposure to excessive extracellular glutamate is shown to be involved in neuronal cell death in acute brain injury and a number of neurological diseases. High concentration of glutamate induces calcium deregulation which results in mitochondrial calcium ov...

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Bibliografski detalji
Izdano u:Mol Neurobiol
Glavni autori: Angelova, Plamena R., Vinogradova, Darya, Neganova, Margarita E., Serkova, Tatiana P., Sokolov, Vladimir V., Bachurin, Sergey O., Shevtsova, Elena F., Abramov, Andrey Y.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6394642/
https://ncbi.nlm.nih.gov/pubmed/30008072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1204-8
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