Inorganic Polyphosphate Regulates AMPA and NMDA Receptors and Protects Against Glutamate Excitotoxicity via Activation of P2Y Receptors

Glutamate is one of the most important neurotransmitters in the process of signal transduction in the CNS. Excessive amounts of this neurotransmitter lead to glutamate excitotoxicity, which is accountable for neuronal death in acute neurological disorders, including stroke and trauma, and in neurode...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Maiolino, Marta, O'Neill, Nathanael, Lariccia, Vincenzo, Amoroso, Salvatore, Sylantyev, Sergiy, Angelova, Plamena R., Abramov, Andrey Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668208/
https://ncbi.nlm.nih.gov/pubmed/31147524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0314-19.2019
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