Laquinimod ameliorates excitotoxic damage by regulating glutamate re-uptake

BACKGROUND: Laquinimod is an immunomodulatory drug under clinical investigation for the treatment of the progressive form of multiple sclerosis (MS) with both anti-inflammatory and neuroprotective effects. Excitotoxicity, a prominent pathophysiological feature of MS and of its animal model, experime...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Gentile, Antonietta, Musella, Alessandra, De Vito, Francesca, Fresegna, Diego, Bullitta, Silvia, Rizzo, Francesca Romana, Centonze, Diego, Mandolesi, Georgia
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756343/
https://ncbi.nlm.nih.gov/pubmed/29304807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1048-6
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