Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

Prophylactic vaccination of rhesus macaques (RM) with rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) elicits immune responses that stringently control highly pathogenic SIV infection, with subsequent apparent clearance of the infection, in...

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Vydáno v:Nat Med
Hlavní autoři: Okoye, Afam A., Hansen, Scott G., Vaidya, Mukta, Fukazawa, Yoshinori, Park, Haesun M., Duell, Derick M., Lum, Richard, Hughes, Colette M., Ventura, Abigail B., Ainslie, Emily, Ford, Julia C., Morrow, David, Gilbride, Roxanne M., Legasse, Alfred W., Hesselgesser, Joseph, Geleziunas, Romas, Li, Yuan, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J., Borate, Bhavesh R., Edlefsen, Paul T., Axthelm, Michael K., Picker, Louis J., Lifson, Jeffrey D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389357/
https://ncbi.nlm.nih.gov/pubmed/30082858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0130-7
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