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Inhibitors of HIF-1α and CXCR4 Mitigate the Development of Radiation Necrosis in Mouse Brain
PURPOSE: There is mounting evidence that, in addition to angiogenesis, hypoxia-induced inflammation via the hypoxia-inducible factor 1α (HIF-1α)–CXC chemokine receptor 4 (CXCR4) pathway may contribute to the pathogenesis of late-onset, irradiation-induced necrosis. This study investigates the mitiga...
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| izdano v: | Int J Radiat Oncol Biol Phys |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6389273/ https://ncbi.nlm.nih.gov/pubmed/29485043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2017.12.257 |
| Oznake: |
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