IMMU-05. LATE EFFECTS OF INTRACRANIAL RADIATION INDUCES RESISTANCE TO IMMUNE CHECKPOINT BLOCKADE THERAPY THAT IS PARTIALLY REVERSIBLE WITH CSF-1R INHIBITION

Primary and metastatic CNS malignancies remain incurable despite aggressive therapy with surgery and radiation. Immunotherapy has shown promise in many solid and hematologic malignancies, however, results have been disappointing in recurrent primary CNS tumors. Additionally, while upfront immune che...

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Publié dans:Neuro Oncol
Auteurs principaux: Johanns, Tanner, Yuan, Liya, Engelbach, John, Dunn, Gavin, Thotala, Dinesh, Beeman, Scott, Tsien, Christina, Ackerman, Joseph, Garbow, Joel
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217337/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.508
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