IMMU-05. LATE EFFECTS OF INTRACRANIAL RADIATION INDUCES RESISTANCE TO IMMUNE CHECKPOINT BLOCKADE THERAPY THAT IS PARTIALLY REVERSIBLE WITH CSF-1R INHIBITION

Primary and metastatic CNS malignancies remain incurable despite aggressive therapy with surgery and radiation. Immunotherapy has shown promise in many solid and hematologic malignancies, however, results have been disappointing in recurrent primary CNS tumors. Additionally, while upfront immune che...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Johanns, Tanner, Yuan, Liya, Engelbach, John, Dunn, Gavin, Thotala, Dinesh, Beeman, Scott, Tsien, Christina, Ackerman, Joseph, Garbow, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217337/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.508
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