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BRAF-MEK inhibitors as steroid-sparing bridge prior to checkpoint blockade therapy in symptomatic intracranial melanoma

The introduction of immune checkpoint blockade (ICB) and BRAF-MEK inhibitors has substantially improved outcomes in patients with metastatic melanoma. However, several challenging factors may hinder the efficacy of ICB in patients with symptomatic intracranial metastatic melanoma who are immunosuppr...

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Bibliografiske detaljer
Udgivet i:Melanoma Manag
Main Authors: Khaddour, Karam, Johanns, Tanner M, Ansstas, George
Format: Artigo
Sprog:Inglês
Udgivet: Future Medicine Ltd 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162174/
https://ncbi.nlm.nih.gov/pubmed/34084449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/mmt-2020-0022
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