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BRAF-MEK inhibitors as steroid-sparing bridge prior to checkpoint blockade therapy in symptomatic intracranial melanoma

The introduction of immune checkpoint blockade (ICB) and BRAF-MEK inhibitors has substantially improved outcomes in patients with metastatic melanoma. However, several challenging factors may hinder the efficacy of ICB in patients with symptomatic intracranial metastatic melanoma who are immunosuppr...

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Detalles Bibliográficos
Publicado en:Melanoma Manag
Main Authors: Khaddour, Karam, Johanns, Tanner M, Ansstas, George
Formato: Artigo
Idioma:Inglês
Publicado: Future Medicine Ltd 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162174/
https://ncbi.nlm.nih.gov/pubmed/34084449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/mmt-2020-0022
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