Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation

Despite the substantial advances in the management of metastatic melanoma with the introduction of immune checkpoint inhibitors (ICI), many patients develop disease progression during treatment with immunotherapy. This has been suggested to be mediated by several mechanisms that contribute to acquir...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Khaddour, Karam, Dowling, Joshua, Huang, Jiayi, Council, Martha, Chen, David, Cornelius, Lynn, Johanns, Tanner, Dahiya, Sonika, Ansstas, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2020
Schlagworte:
Case Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779252/
https://ncbi.nlm.nih.gov/pubmed/33447351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27848
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