Can anti-Vascular Endothelial Growth Factor Antibody Reverse Radiation Necrosis? A Preclinical Investigation

Anti-vascular endothelial growth factor (anti-VEGF) antibodies are a promising new treatment for late time-to-onset radiation-induced necrosis (RN). We sought to evaluate and validate the response to anti-VEGF antibody in a mouse model of RN. Mice were irradiated with the Leksell Gamma Knife Perfexi...

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Bibliografiske detaljer
Udgivet i:J Neurooncol
Main Authors: Duan, Chong, Perez-Torres, Carlos J, Yuan, Liya, Engelbach, John A, Beeman, Scott C, Tsien, Christina I, Rich, Keith M, Schmidt, Robert E, Ackerman, Joseph JH, Garbow, Joel R
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548457/
https://ncbi.nlm.nih.gov/pubmed/28425047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-017-2410-3
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