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Kv4.3 expression abrogates and reverses norepinephrine-induced myocyte hypertrophy by CaMKII inhibition

BACKGROUND: Down-regulation of Kv4.3 protein is a general feature of cardiac hypertrophy. Based on our recent studies, we propose that Kv4.3 reduction may be a hypertrophic stimulator. OBJECTIVE: We tested whether Kv4.3 expression can prevent or reverse cardiac hypertrophy induced by norepinephrine...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Wang, Yanggan, Keskanokwong, Thitima, Cheng, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387688/
https://ncbi.nlm.nih.gov/pubmed/30462989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.11.011
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