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Alterations of L-type Calcium Current and Cardiac Function in CaMKIIδ Knockout Mice

RATIONALE: Recent studies have highlighted important roles of CaMKII in regulating Ca(2+) handling and excitation-contraction coupling. However, the cardiac effect of chronic CaMKII inhibition has not been well understood. OBJECTIVE: We have tested the alterations of L-type calcium current (I(Ca)) a...

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Detalhes bibliográficos
Main Authors: Xu, Lin, Lai, Dongwu, Cheng, Jun, Lim, Hyun Joung, Keskanokwong, Thitima, Backs, Johannes, Olson, Eric N., Wang, Yanggan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923749/
https://ncbi.nlm.nih.gov/pubmed/20538682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.222562
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