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Abnormal glycogen storage in tuberous sclerosis complex caused by impairment of mTORC1-dependent and -independent signaling pathways

Tuberous sclerosis complex (TSC) is an autosomal dominant syndrome that causes tumor formation in multiple organs. TSC is caused by inactivating mutations in the genes encoding TSC1/2, negative regulators of the mammalian target of rapamycin complex 1 (mTORC1). Diminished TSC function is associated...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Pal, Rituraj, Xiong, Yan, Sardiello, Marco
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386676/
https://ncbi.nlm.nih.gov/pubmed/30728291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812943116
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