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Drosophila melanogaster nonribosomal peptide synthetase Ebony encodes an atypical condensation domain

The protein Ebony from Drosophila melanogaster plays a central role in the regulation of histamine and dopamine in various tissues through condensation of these amines with β-alanine. Ebony is a rare example of a nonribosomal peptide synthetase (NRPS) from a higher eukaryote and contains a C-termina...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Izoré, Thierry, Tailhades, Julien, Hansen, Mathias Henning, Kaczmarski, Joe A., Jackson, Colin J., Cryle, Max J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386674/
https://ncbi.nlm.nih.gov/pubmed/30705105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811194116
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