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Copper-catalyzed oxidative benzylic C-H cyclization via iminyl radical from intermolecular anion-radical redox relay

Base-promoted C-H cleavage without transition metals opens a practical alternative for the one based on noble metals or radical initiators. The resulting carbanion can pass through radical addition to unsaturated bonds like C-N or C-C triple bonds, in which stoichiometric oxidants are needed. When i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Shan, Xiang-Huan, Zheng, Hong-Xing, Yang, Bo, Tie, Lin, Fu, Jia-Le, Qu, Jian-Ping, Kang, Yan-Biao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385223/
https://ncbi.nlm.nih.gov/pubmed/30796224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08849-z
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