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Cross-Presentation of Skin-Targeted Recombinant Adeno-associated Virus 2/1 Transgene Induces Potent Resident Memory CD8(+) T Cell Responses

A key aspect to consider for vaccinal protection is the induction of a local line of defense consisting of nonrecirculating tissue-resident memory T cells (T(RM)), in parallel to the generation of systemic memory CD8(+) T cell responses. The potential to induce T(RM) has now been demonstrated for a...

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發表在:J Virol
Main Authors: Gross, David-Alexandre, Ghenassia, Alexandre, Bartolo, Laurent, Urbain, Dominique, Benkhelifa-Ziyyat, Sofia, Lorain, Stéphanie, Davoust, Jean, Chappert, Pascal
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384067/
https://ncbi.nlm.nih.gov/pubmed/30541847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01334-18
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