PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

By engulfing potentially harmful microbes, professional phagocytes are continually at risk from intracellular pathogens. To avoid becoming infected, the host must kill pathogens in the phagosome before they can escape or establish a survival niche. Here, we analyse the role of the phosphoinositide (...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Buckley, Catherine M., Heath, Victoria L., Guého, Aurélie, Bosmani, Cristina, Knobloch, Paulina, Sikakana, Phumzile, Personnic, Nicolas, Dove, Stephen K., Michell, Robert H., Meier, Roger, Hilbi, Hubert, Soldati, Thierry, Insall, Robert H., King, Jason S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382210/
https://ncbi.nlm.nih.gov/pubmed/30730983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007551
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge