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Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transport

A series of fluorinated tripodal tris-thioureas function as highly active anion transporters across lipid bilayers and cell membranes. Here, we investigate their mechanism of action using anion transport assays in cells and synthetic vesicles and molecular modelling of transporter–lipid interactions...

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Foilsithe in:Chem Sci
Main Authors: Spooner, Michael J., Li, Hongyu, Marques, Igor, Costa, Pedro M. R., Wu, Xin, Howe, Ethan N. W., Busschaert, Nathalie, Moore, Stephen J., Light, Mark E., Sheppard, David N., Félix, Vítor, Gale, Philip A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Royal Society of Chemistry 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381411/
https://ncbi.nlm.nih.gov/pubmed/30881627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05155k
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