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Tilting and Tumbling in Transmembrane Anion Carriers: Activity Tuning through n‐Alkyl Substitution

Anion transport by synthetic carriers (anionophores) holds promise for medical applications, especially the treatment of cystic fibrosis. Among the factors which determine carrier activity, the size and disposition of alkyl groups is proving remarkably important. Herein we describe a series of dithi...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Edwards, Sophie J., Marques, Igor, Dias, Christopher M., Tromans, Robert A., Lees, Nicholas R., Félix, Vítor, Valkenier, Hennie, Davis, Anthony P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064602/
https://ncbi.nlm.nih.gov/pubmed/26748870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201504057
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