Tilting and Tumbling in Transmembrane Anion Carriers: Activity Tuning through n‐Alkyl Substitution

Anion transport by synthetic carriers (anionophores) holds promise for medical applications, especially the treatment of cystic fibrosis. Among the factors which determine carrier activity, the size and disposition of alkyl groups is proving remarkably important. Herein we describe a series of dithi...

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Publicado en:Chemistry
Autores principales: Edwards, Sophie J., Marques, Igor, Dias, Christopher M., Tromans, Robert A., Lees, Nicholas R., Félix, Vítor, Valkenier, Hennie, Davis, Anthony P.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064602/
https://ncbi.nlm.nih.gov/pubmed/26748870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201504057
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