An in vivo screen identifies PYGO2 as a driver for metastatic prostate cancer

Advanced prostate cancer displays conspicuous chromosomal instability and rampant copy number aberrations, yet the identity of functional drivers resident in many amplicons remain elusive. Here, we implemented a functional genomics approach to identify new oncogenes involved in prostate cancer progr...

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Опубликовано в: :Cancer Res
Главные авторы: Lu, Xin, Pan, Xiaolu, Wu, Chang-Jiun, Zhao, Di, Feng, Shan, Zang, Yong, Lee, Rumi, Khadka, Sunada, Amin, Samirkumar B., Jin, Eun-Jung, Shang, Xiaoying, Deng, Pingna, Luo, Yanting, Morgenlander, William R., Weinrich, Jacqueline, Lu, Xuemin, Jiang, Shan, Chang, Qing, Navone, Nora M., Troncoso, Patricia, DePinho, Ronald A., Wang, Y. Alan
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381393/
https://ncbi.nlm.nih.gov/pubmed/29769196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3564
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