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Precision medicine review: rare driver mutations and their biophysical classification

How can biophysical principles help precision medicine identify rare driver mutations? A major tenet of pragmatic approaches to precision oncology and pharmacology is that driver mutations are very frequent. However, frequency is a statistical attribute, not a mechanistic one. Rare mutations can als...

詳細記述

保存先:
書誌詳細
出版年:Biophys Rev
主要な著者: Nussinov, Ruth, Jang, Hyunbum, Tsai, Chung-Jung, Cheng, Feixiong
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381362/
https://ncbi.nlm.nih.gov/pubmed/30610579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-018-0496-2
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