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TLR4 signaling improves PD-1 blockade therapy during chronic viral infection
CD8 T cells are necessary for the elimination of intracellular pathogens, but during chronic viral infections, CD8 T cells become exhausted and unable to control the persistent infection. Programmed cell death-1 (PD-1) blockade therapies have been shown to improve CD8 T cell responses during chronic...
Uloženo v:
| Vydáno v: | PLoS Pathog |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380600/ https://ncbi.nlm.nih.gov/pubmed/30726291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007583 |
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