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TLR4 signaling improves PD-1 blockade therapy during chronic viral infection
CD8 T cells are necessary for the elimination of intracellular pathogens, but during chronic viral infections, CD8 T cells become exhausted and unable to control the persistent infection. Programmed cell death-1 (PD-1) blockade therapies have been shown to improve CD8 T cell responses during chronic...
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| Publicado en: | PLoS Pathog |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380600/ https://ncbi.nlm.nih.gov/pubmed/30726291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007583 |
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