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Early type I IFN blockade improves the efficacy of viral vaccines
Type I interferons (IFN-I) are a major antiviral defense and are critical for the activation of the adaptive immune system. However, early viral clearance by IFN-I could limit antigen availability, which could in turn impinge upon the priming of the adaptive immune system. In this study, we hypothes...
Uloženo v:
| Vydáno v: | J Exp Med |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Rockefeller University Press
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7953731/ https://ncbi.nlm.nih.gov/pubmed/32820330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191220 |
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