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Early type I IFN blockade improves the efficacy of viral vaccines

Type I interferons (IFN-I) are a major antiviral defense and are critical for the activation of the adaptive immune system. However, early viral clearance by IFN-I could limit antigen availability, which could in turn impinge upon the priming of the adaptive immune system. In this study, we hypothes...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Palacio, Nicole, Dangi, Tanushree, Chung, Young Rock, Wang, Yidan, Loredo-Varela, Juan Luis, Zhang, Zhongyao, Penaloza-MacMaster, Pablo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953731/
https://ncbi.nlm.nih.gov/pubmed/32820330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191220
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