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Detecting repeated cancer evolution in human tumours from multi-region sequencing data

Cancer evolution is driven by the accumulation of (epi)genomic aberrations. Recurrent sequences of genomic changes, between and within patients, reflect repeated evolution that is valuable for anticipating cancer progression. Multi-region sequencing allows inference of some temporal orderings of gen...

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Dades bibliogràfiques
Publicat a:Nat Methods
Autors principals: Caravagna, Giulio, Giarratano, Ylenia, Ramazzotti, Daniele, Tomlinson, Ian, Graham, Trevor A, Sanguinetti, Guido, Sottoriva, Andrea
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380470/
https://ncbi.nlm.nih.gov/pubmed/30171232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0108-x
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