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Detecting repeated cancer evolution in human tumours from multi-region sequencing data

Cancer evolution is driven by the accumulation of (epi)genomic aberrations. Recurrent sequences of genomic changes, between and within patients, reflect repeated evolution that is valuable for anticipating cancer progression. Multi-region sequencing allows inference of some temporal orderings of gen...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Caravagna, Giulio, Giarratano, Ylenia, Ramazzotti, Daniele, Tomlinson, Ian, Graham, Trevor A, Sanguinetti, Guido, Sottoriva, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380470/
https://ncbi.nlm.nih.gov/pubmed/30171232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0108-x
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