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The MOBSTER R package for tumour subclonal deconvolution from bulk DNA whole-genome sequencing data

BACKGROUND: The large-scale availability of whole-genome sequencing profiles from bulk DNA sequencing of cancer tissues is fueling the application of evolutionary theory to cancer. From a bulk biopsy, subclonal deconvolution methods are used to determine the composition of cancer subpopulations in t...

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Bibliografiset tiedot
Julkaisussa:BMC Bioinformatics
Päätekijät: Caravagna, Giulio, Sanguinetti, Guido, Graham, Trevor A., Sottoriva, Andrea
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672894/
https://ncbi.nlm.nih.gov/pubmed/33203356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03863-1
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