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Detecting repeated cancer evolution in human tumours from multi-region sequencing data

Cancer evolution is driven by the accumulation of (epi)genomic aberrations. Recurrent sequences of genomic changes, between and within patients, reflect repeated evolution that is valuable for anticipating cancer progression. Multi-region sequencing allows inference of some temporal orderings of gen...

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Bibliografiske detaljer
Udgivet i:Nat Methods
Main Authors: Caravagna, Giulio, Giarratano, Ylenia, Ramazzotti, Daniele, Tomlinson, Ian, Graham, Trevor A, Sanguinetti, Guido, Sottoriva, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380470/
https://ncbi.nlm.nih.gov/pubmed/30171232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0108-x
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