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Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities

Antibodies provide immune protection by recognizing antigens of diverse chemical properties, but elucidating the amino acid sequence-function relationships underlying the specificity and affinity of antibody-antigen interactions remains challenging. We designed and constructed phage-displayed synthe...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Jian, Jhih-Wei, Chen, Hong-Sen, Chiu, Yi-Kai, Peng, Hung-Pin, Tung, Chao-Ping, Chen, Ing-Chien, Yu, Chung-Ming, Tsou, Yueh-Liang, Kuo, Wei-Ying, Hsu, Hung-Ju, Yang, An-Suei
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380391/
https://ncbi.nlm.nih.gov/pubmed/30526270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1550320
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