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Origins of specificity and affinity in antibody–protein interactions

Natural antibodies are frequently elicited to recognize diverse protein surfaces, where the sequence features of the epitopes are frequently indistinguishable from those of nonepitope protein surfaces. It is not clearly understood how the paratopes are able to recognize sequence-wise featureless epi...

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Detalhes bibliográficos
Main Authors: Peng, Hung-Pin, Lee, Kuo Hao, Jian, Jhih-Wei, Yang, An-Suei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084487/
https://ncbi.nlm.nih.gov/pubmed/24938786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401131111
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