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Origins of specificity and affinity in antibody–protein interactions

Natural antibodies are frequently elicited to recognize diverse protein surfaces, where the sequence features of the epitopes are frequently indistinguishable from those of nonepitope protein surfaces. It is not clearly understood how the paratopes are able to recognize sequence-wise featureless epi...

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Bibliographic Details
Main Authors: Peng, Hung-Pin, Lee, Kuo Hao, Jian, Jhih-Wei, Yang, An-Suei
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084487/
https://ncbi.nlm.nih.gov/pubmed/24938786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401131111
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