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PinMol: Python application for designing molecular beacons for live cell imaging of endogenous mRNAs

Molecular beacons are nucleic acid oligomers labeled with a fluorophore and a quencher that fold in a hairpin-shaped structure, which fluoresce only when bound to their target RNA. They are used for the visualization of endogenous mRNAs in live cells. Here, we report a Python program (PinMol) that d...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Bayer, Livia V., Omar, Omar S., Bratu, Diana P., Catrina, Irina E.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380279/
https://ncbi.nlm.nih.gov/pubmed/30573696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.069542.118
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