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tRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells

When oligonucleotide probes are microinjected into cells to image the distribution of RNAs, they are rapidly sequestered into the nucleus. As a result, it is difficult to detect mRNAs in the cytoplasm of living cells. We were able to overcome this process by attaching tRNA transcripts to the probes....

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Mhlanga, Musa M., Vargas, Diana Y., Fung, Cindy W., Kramer, Fred Russell, Tyagi, Sanjay
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1074395/
https://ncbi.nlm.nih.gov/pubmed/15809226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki302
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