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Visualizing the distribution and transport of mRNAs in living cells

We have visualized the movements of native mRNAs in living cells. Using nuclease-resistant molecular beacons, we imaged the transport and localization of oskar mRNA in Drosophila melanogaster oocytes. When the localization pattern was altered by genetic manipulation of the mRNA's 3′ untranslate...

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Main Authors: Bratu, Diana P., Cha, Byeong-Jik, Mhlanga, Musa M., Kramer, Fred Russell, Tyagi, Sanjay
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC263795/
https://ncbi.nlm.nih.gov/pubmed/14583593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2233244100
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