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Molecular beacon enabled purification of living cells by targeting cell-type specific mRNAs

Molecular beacons (MBs) are dual-labeled oligonucleotides that fluoresce only in the presence of complementary mRNA. The use of MBs to target specific mRNAs allows sorting of specific cells from a mixed cell population. In contrast to existing approaches that are limited by available surface markers...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Wile, Brian M., Ban, Kiwon, Yoon, Young-Sup, Bao, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326061/
https://ncbi.nlm.nih.gov/pubmed/25232937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.154
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